Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles

• Peter Wipf and
• Marija D. Manojlovic

Beilstein J. Org. Chem. 2011, 7, 824–830, doi:10.3762/bjoc.7.94

• chloride provides functionalized homoallylic amines. An intramolecular version of this process leads to 3-aminotetrahydrofurans and 3-aminotetrahydropyrans. Keywords: allene; 3-aminotetrahydrofurans; 3- and 4-aminotetrahydropyrans; hydrozirconation; nitrile; transmetalation; Introduction The reversible